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Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website. PDE5 inhibitors like sildenafil work by blocking an enzyme called PDE5, which makes blood vessels smaller. During an erection, a natural chemical called cGMP opens up blood vessels in the penis, increasing blood flow and making the penis harder. Since PDE5 stops cGMP (therefore blocking erections), inhibiting PDE5 allows cGMP to work its magic and make erections last longer (Smith, 2021).

If use of a nitrate-containing medication is considered medically necessary, you must wait 48 hours after the last dose of sildenafil before taking a nitrate, and only under close medical supervision. Other medical conditions you have can also affect your Viagra dosage. Specifically, you may have a lower starting dosage than usual if you’re over age 65. For example, a 30-year-old might start at a dose of 50 milligrams (mg), while a 70-year-old might have a starting dose of 25 mg.

Large meals and high-fat foods are not recommended as they prevent Viagra from being metabolised quickly or effectively. If you’ve already eaten, it’s best that you wait a few hours for the food to digest first. ED is common amongst men above the age of 40, and can be a result of either type-2 diabetes or high blood pressure. That said, younger men are not immune to developing ED, especially when under huge psychological stress. Erectile dysfunction (ED) is a sexual dysfunction whereby men are unable to achieve or maintain an erection for sexual intercourse.

Following at least 14 consecutive daily doses of doxazosin, VIAGRA 100 mg or matching placebo was administered simultaneously with doxazosin. Following a review of the data from these first 4 subjects (details provided below), the VIAGRA dose was reduced to 25 mg. Thereafter, 17 subjects were treated with VIAGRA 25 mg or matching placebo in combination with doxazosin 4 mg (15 subjects) or doxazosin 8 mg (2 subjects). Limited data indicate that sildenafil and its active metabolite are present in human milk. There is no information on the effects on the breastfed child, or the effects on milk production. The following adverse reactions have been identified during post approval use of VIAGRA.

If the prescribed dosage of Viagra works well for you and doesn’t cause bothersome side effects, you’ll likely continue taking it. If a dosage works well but causes bothersome side effects, your doctor may suggest a lower dosage. If a dosage doesn’t work to help you get or maintain an erection, your doctor may increase your dosage.

When buying sildenafil online, beware of counterfeit drugs. Many online ads promising Viagra for cents on the dollar are not legit, and the product they sell can be dangerous. They can contain too little or too much sildenafil, contaminants, and other substances. If you take medications to lower high blood pressure (antihypertensives), taking Viagra can cause your blood pressure to drop even further.

Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of VIAGRA. Although the interaction between other protease inhibitors and sildenafil has not been studied, their concomitant use is expected to increase sildenafil levels. Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with VIAGRA (50 mg) to healthy volunteers. In addition, N-desmethyl metabolite AUC and Cmax values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function. The mean profiles of the change from baseline in standing systolic blood pressure in subjects treated with doxazosin in combination with 100 mg VIAGRA or matching placebo are shown in Figure 4.

Doctors recommend trying it at least eight times before making any changes. Factors like alcohol consumption, meal timing, and mental state can influence the medication's effectiveness. If Sildenafil 100mg isn't working effectively, ensure you're taking it correctly as prescribed and discuss potential dosage or timing adjustments with your doctor. When considering Sildenafil (Viagra) for erectile dysfunction (ED), the right dosage can make a significant difference in its performance. So, it's important to understand how to choose the right option for your needs.

You shouldn’t take Viagra with illegal drugs called poppers. Poppers contain nitrate drugs such as amyl nitrate, alkyl nitrate, and butyl nitrate. Taking Viagra with poppers can cause a dangerous drop in your blood pressure that can lead to heart attack or stroke. However, if you have high blood pressure that’s managed with medication and you also don’t have a heart condition, it’s usually fine to take Viagra.

A causal relationship between VIAGRA and these events has not been established. In humans, VIAGRA has no effect on bleeding time when taken alone or with aspirin. However, in vitro studies with human platelets indicate that sildenafil potentiates the antiaggregatory effect of sodium nitroprusside (a nitric oxide donor). In addition, the combination of heparin and VIAGRA had an additive effect on bleeding time in the anesthetized rabbit, but this interaction has not been studied in humans.

Store the suspension at room temperature or in a refrigerator, but do not freeze it. Patients should always ask their doctors for medical advice about adverse events. Your prescription may have been filled with a generic version instead of brand-name VIAGRA.

Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe. LAMOTRIGINE (la MOE tri jeen) prevents and controls seizures in people with epilepsy. If you know the name of the ED medication you are looking to purchase, you can search online or through the app on your Apple or Android device. Our health benefit plans have exclusions and limitations and terms under which the coverage may be continued in force or discontinued. For costs and complete details of the coverage, refer to the plan document or call or write your Humana insurance agent or the company.

Sildenafil at recommended doses has no effect in the absence of sexual stimulation. In fixed-dose studies, the incidence of some adverse reactions increased with dose. The type of adverse reactions in flexible-dose studies, which reflect the recommended dosage regimen, was similar to that for fixed-dose studies. At doses above the recommended dose range, adverse reactions were similar to those detailed in Table 1 below but generally were reported more frequently.

Sildenafil100 mg belongs to a group of medicines called phosphodiesterase type5 (PDE 5) inhibitors. It works by helping to relax the blood vessels in yourpenis, allowing blood to flow into your penis when you get sexually excited. Sildenafil&nbsp